evaluation of fluticasone (flixonase) nasal spray versus beclomethasone (beconase) nasal spray in the treatment of allergic rhinitis
نویسندگان
چکیده
although response to intranasal steroid therapy has been reported in pa¬tients with allergic rhinitis, efficacy of some nasal steroids is noteworthy. this study was undertaken to evaluate the efficacy of a two-week course of fluticasone (flixonase) nasal spray vs. beclomethasone (beconase) nasal spray in patients with symptoms of allergic rhinitis referred to our clinic. this study reviewed sixty randomized studies with symptoms of allergic rhinitis which sup¬ported common aeroallergens with skin prick test. patients received a total daily dose of nasal spray of fluticasone (flixonase) 100 meg bid (n=30) compared with patients with allergic rhinitis who received a total daily dose of beclomethasone (beconase) 50mcg 2 puffs bid (n=30). patients were visited before and after therapy, and efficacy of flixonase. and beconase was evaluated by the change in nasal symptoms including: nasal discharge, nasal obstruction, nasal itching, and sneezing. after two weeks of treatment nasal symptoms of blockage, discharge, sneezing and itching were significantly better in the group treated with fluticasone nasal spray (65%, 82%, 67%, 79% respectively (/? 100 meg bid flixonase (fluticasone) intranasal spray is more effective than 50 meg 2 puffs bid beconase (beclomethasone) intranasal spray. like asthma, allergic rhinitis is an inflammatory disease and should be managed with anti-in¬flammatory medication.
منابع مشابه
Fluticasone furoate nasal spray in the treatment of allergic rhinitis
Allergic rhinitis (AR) is a prevalent disease with great morbidity and significant societal and economic burden. Intranasal corticosteroids are recommended as first-line therapy for patients with moderate-to-severe disease, especially when nasal congestion is a major component of symptoms. To compare the efficacy and safety profile of different available intranasal corticosteroids for the treat...
متن کاملCost-effectiveness analysis of budesonide aqueous nasal spray and fluticasone propionate nasal spray in the treatment of perennial allergic rhinitis.
BACKGROUND An economic evaluation was performed analyzing direct medical costs in Canada for the treatment of perennial allergic rhinitis (PAR) with budesonide aqueous nasal spray and fluticasone propionate nasal spray. Three hundred fourteen patients with at least a 1-year history of PAR were randomized into a double-blind, parallel-group study of 6 weeks' duration. The treatments were daily d...
متن کاملComparative efficacy of steroid nasal spray versus antihistamine nasal spray in allergic rhinitis.
This prospective randomized case controlled study was conducted to determine the efficacy of antihistamine (azelastine) nasal spray and compare it to steroid (beclomethasone) nasal spray on the symptoms of allergic rhinitis. Seventy five symptomatic patients of allergic rhinitis were included in this study. Diagnosis was made on the basis of history and physical examination. The patients were d...
متن کاملA comparison of beclomethasone dipropionate aqueous nasal spray and beclomethasone dipropionate pressurized nasal spray in the management of seasonal rhinitis.
Forty patients with seasonal rhinitis and a proven sensitivity to pollens were studied for 2 weeks during the pollen season of 1982. The study was carried out according to a double-blind, double-dummy design. All patients received 100 micrograms beclomethasone dipropionate (BDP) into each nostril twice daily (400 micrograms/day) on a randomized basis, from either the aqueous nasal spray or the ...
متن کاملFluticasone furoate nasal spray: Profile of an enhanced-affinity corticosteroid in treatment of seasonal allergic rhinitis
Of the classes of pharmacotherapy for seasonal allergic rhinitis, intranasal corticosteroids are the preferred treatment and are recommended in practice guidelines as first-line pharmacotherapy for rhinitis with prominent nasal congestion. The enhanced-affinity intranasal corticosteroid fluticasone furoate nasal spray (GW685698X), is one of the newest additions to the armamentarium for allergic...
متن کاملEfficacy of a steroid nasal spray compared with an antihistamine nasal spray in the treatment of perennial allergic rhinitis.
Allergic rhinitis is a common disease with a lifetime prevalence of 20% among the United States population. The cost of medication alone to manage allergic rhinitis in the United States was estimated to be $3.1 billion. The two most commonly prescribed classes of medications are antihistamines and topical nasal steroids. The data on comparing the efficacy of a commonly used antihistamine (azela...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
iranian journal of allergy, asthma and immunologyجلد ۲، شماره ۴، صفحات ۱۹۳-۱۹۶
کلمات کلیدی
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023